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Bone marrow resident Macs Osteomacs
2019-05-31
Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow toll like receptors and
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ER provides the clinician with
2019-05-31
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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A previous study reported that patients with early
2019-05-31
A previous study reported that patients with early AF recurrences were significantly less likely to have long-term freedom from recurrent AF than patients without early recurrences [3]. In the present study, landiolol administration tended to improve the mid-term prognosis compared to placebo. In a
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More than structural haemoglobin variants
2019-05-31
More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino trpv1 antagonist (β99 Asp→Tyr) involved in the stability
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Idelalisib demonstrates a dual mechanism of action
2019-05-31
Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour cycloastragenol by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protectiv
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Another mechanism is that J waves represent
2019-05-31
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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In addition to CAF in the primary
2019-05-31
In addition to CAF in the primary tumour microenvironment, it is tempting to speculate that fibroblasts within the bone itself may play a role in the establishment of metastatic deposits. Fibroblasts form a major component of the bone marrow stroma and regulate haematopoiesis by secreting a range of
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br Discussion We describe an additional diagnosis to conside
2019-05-31
Discussion We describe an additional diagnosis to consider when BVT is identified. One of the proposed mechanisms of BVT include elevated intracellular calcium, causing delay after depolarization in anatomically separate parts of the conducting system. Baher et al. [1] proposed that two separate
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En la obra de Cuadra una familia campesina confronta
2019-05-30
En la obra de Cuadra, una familia campesina confronta trágicamente la guerra civil entre conservadores y liberales. Víctimas pasivas de las élites y no actores políticos, estos campesinos ven cómo los principios familiares tradicionales y del minifundio son desarticulados por la guerra y el abuso de
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Percebemos ent o tentando tra ar uma linha que
2019-05-30
Percebemos, então, tentando traçar uma linha que amarre as discussões dos intelectuais mencionados, que as revoluções cubana e sandinista foram representadas positivamente na revista Araucaria de Chile, através de argumentos relacionados ao desenvolvimento e à popularização da cultura após apexbio d
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Entretanto quando as elei es
2019-05-30
Entretanto, quando as eleições presidenciais se aproximaram em 1990 o país vivia um momento bastante diferente, marcado não somente pelos agudos problemas econômicos já descritos, mas também pelo incremento da ação militar urbana de Sendero Luminoso, uma vez que make film. partir de 1989 sua lideran
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br La flor de Coleridge En el ensayo de ese
2019-05-30
La flor de Coleridge En el ensayo de ese nombre contenido en Otras inquisiciones leemos: De inmediato, y como corolario de estas ideas, nuestro ensayista da un salto para instalarnos en un mundo donde esta probabilidad se cumple: Como en el universo de Tlön, y siguiendo las premisas del idealis
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br Case report We report a case of
2019-05-30
Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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Dyslipidemia is characterized by increased total cholesterol
2019-05-30
Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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br Methods br Results A
2019-05-30
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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