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natriuretic peptide receptor Studies of strategies to reduce
2019-05-10
Studies of strategies to reduce greenhouse gas emissions and improve health in urban environments have shown the potential to achieve both environmental and health improvements. For example, modelled effects of low emission vehicles and increased walking and cycling in London and Delhi showed major
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br Methods br Results br Discussion br Conclusions
2019-05-10
Methods Results Discussion Conclusions Author contributions Disclosures and funding sources Conflicts of interest Introduction Head-up tilt (HUT) testing has become a widely accepted diagnostic tool for the evaluation of neurally mediated syncope (NMS), which is a major cause
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Introduction Personalized medicine is the major goal of
2019-05-10
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease alkylation of dna and predict clinical outcome. However, to define a specific disease ph
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However during pacing at the
2019-05-09
However, during pacing at the most proximal CS electrodes (CS 9–10), although the conduction time to the CS 1–2 was prolonged, the septal to lateral activation sequence (CS 5–6 to CS 3–4 to CS 1–2) indicated the presence of residual conduction on the MI line (Fig. 3B). Detailed mapping on the MI lin
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br Hybrid approach It is still not
2019-05-09
Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc
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br Grant support This work was supported by
2019-05-09
Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20
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More recently primary tumor driven generation of a bone pre
2019-05-09
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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Como es l gico hay un personaje que hace de
2019-05-09
Como es lógico, hay un personaje que hace de contrapunto order Metformin esa posición y que por ello mismo la vuelve, por efecto de una diférance (Derrida 1972b), mucho más significativa. Lily, la mujer de Nicolás, no comprende ni lo más mínimo la fascinación que ejerce sobre su marido esa novela. L
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Tobacco use is poised to kill
2019-05-09
Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and
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Introduction The World health organization WHO defines
2019-05-09
Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line
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But consider the alternative outcomes of so called virtuous
2019-05-09
But consider the alternative outcomes of so-called virtuous plate-clearing. If the additional portion does not displace other consumption—ie, the amount eaten subsequently is not reduced—then total consumption will have increased. A lack of displacement means no reduction in demand for agricultural
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br Unacceptably high rates of adverse outcomes
2019-05-09
Unacceptably high rates of adverse outcomes persist for childbearing women and infants, including maternal and newborn mortality, stillbirth, and short-term and long-term morbidity. In light of the challenges to achieve the UN Sustainable Development Goals, it is timely to reconsider priorities fo
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We examined pharmacologic exposures among
2019-05-09
We examined pharmacologic exposures among the subset of women diagnosed with breast cancer on or after 1995 (N=620) and found that over two thirds (70.8%) received adjuvant endocrine therapy prior to hip or interleukin 2 receptor fracture, including 30.8% who received tamoxifen only, 23.1% who rece
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Fer-1 This Ca overload activates the forward
2019-05-09
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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br Case report An year
2019-05-08
Case report An 81-year-old man with ischemic cardiomyopathy underwent ICD all trans retinoic acid for primary prevention in February 2007. The patient had never experienced spontaneous VF. A Riata™ 1570 dual-coiled lead (St. Jude Medical, Sylmar, CA) was passed through the left cephalic vein and
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