• More recently primary tumor driven generation of a bone pre

  2019-05-09

  

  More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i

• Como es l gico hay un personaje que hace de

  2019-05-09

  

  Como es lógico, hay un personaje que hace de contrapunto order Metformin esa posición y que por ello mismo la vuelve, por efecto de una diférance (Derrida 1972b), mucho más significativa. Lily, la mujer de Nicolás, no comprende ni lo más mínimo la fascinación que ejerce sobre su marido esa novela. L

• Tobacco use is poised to kill

  2019-05-09

  

  Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and

• Introduction The World health organization WHO defines

  2019-05-09

  

  Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line

• But consider the alternative outcomes of so called virtuous

  2019-05-09

  

  But consider the alternative outcomes of so-called virtuous plate-clearing. If the additional portion does not displace other consumption—ie, the amount eaten subsequently is not reduced—then total consumption will have increased. A lack of displacement means no reduction in demand for agricultural

• br Unacceptably high rates of adverse outcomes

  2019-05-09

  

  Unacceptably high rates of adverse outcomes persist for childbearing women and infants, including maternal and newborn mortality, stillbirth, and short-term and long-term morbidity. In light of the challenges to achieve the UN Sustainable Development Goals, it is timely to reconsider priorities fo

• We examined pharmacologic exposures among

  2019-05-09

  

  We examined pharmacologic exposures among the subset of women diagnosed with breast cancer on or after 1995 (N=620) and found that over two thirds (70.8%) received adjuvant endocrine therapy prior to hip or interleukin 2 receptor fracture, including 30.8% who received tamoxifen only, 23.1% who rece

• Fer-1 This Ca overload activates the forward

  2019-05-09

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• br Case report An year

  2019-05-08

  

  Case report An 81-year-old man with ischemic cardiomyopathy underwent ICD all trans retinoic acid for primary prevention in February 2007. The patient had never experienced spontaneous VF. A Riata™ 1570 dual-coiled lead (St. Jude Medical, Sylmar, CA) was passed through the left cephalic vein and

• Therefore the patient was diagnosed with

  2019-05-08

  

  Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th

• br La difusi n en Espa a

  2019-05-08

  

  La difusión en España de la Música práctica, impresa en Boloña en 1482 y escrita originalmente en latín, no sólo es innegable, sino decisiva rifampicin lo largo del siglo xvi. Francisco Salinas es un firme defensor de las teorías de Ramos Pareja y, sobre todo, toma su partido en relación con las d

• In Philippe B scher and colleagues present the first

  2019-05-08

  

  In , Philippe Büscher and colleagues present the first formal assessment under field conditions of the HAT Sero--SeT rapid diagnostic test and compared its diagnostic accuracy with two other current serological tests: CATT and immune trypanolysis (a very sensitive and specific test that requires lab

• En la condensaci n del Borges y yo se despliega

  2019-05-08

  

  En la condensación del “Borges y yo” se despliega un texto que tanto puede ser considerado perteneciente al orden de la narrativa como al orden del ensayo, e incluso al de la poesía. En palabras de José Miguel Oviedo, “es un cuento que es también un ensayo que es también un poema”. “No sé quién de l

• Recently emerging data suggest that lower frequency of IV

  2019-05-08

  

  Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f

• Eligio Mar a Ancona Castillo naci en la

  2019-05-07

  

  Eligio María Ancona Castillo nació en la ciudad de Mérida, el 1° de diciembre de 1836. Después de cursar los estudios elementales en la escuela de su padre, inició los cursos preparatorios en el Seminario Conciliar de San Ildefonso. Más tarde se inscribió en la Universidad del Estado para iniciar la

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